The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma

The lack of reliable molecular markers for normal differentiated epithelial cells limits understanding of human gastric carcinogenesis. Recognized precursor lesions for gastric adenocarcinoma are intestinal metaplasia and spasmolytic polypeptide expressing metaplasia (SPEM), defined here by ectopic...

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Detalhes bibliográficos
Main Authors: Lennerz, Jochen K. M., Kim, Seok-Hyung, Oates, Edward L., Huh, Won Jae, Doherty, Jason M., Tian, Xiaolin, Bredemeyer, Andrew J., Goldenring, James R., Lauwers, Gregory Y., Shin, Young-Kee, Mills, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928982/
https://ncbi.nlm.nih.gov/pubmed/20709804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100328
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