The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma

The lack of reliable molecular markers for normal differentiated epithelial cells limits understanding of human gastric carcinogenesis. Recognized precursor lesions for gastric adenocarcinoma are intestinal metaplasia and spasmolytic polypeptide expressing metaplasia (SPEM), defined here by ectopic...

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Main Authors: Lennerz, Jochen K. M., Kim, Seok-Hyung, Oates, Edward L., Huh, Won Jae, Doherty, Jason M., Tian, Xiaolin, Bredemeyer, Andrew J., Goldenring, James R., Lauwers, Gregory Y., Shin, Young-Kee, Mills, Jason C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928982/
https://ncbi.nlm.nih.gov/pubmed/20709804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100328
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