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Maturity and age influence chief cell ability to transdifferentiate into metaplasia
The plasticity of gastric chief cells is exemplified by their ability to transdifferentiate into spasmolytic polypeptide-expressing metaplasia (SPEM) after parietal cell loss. We sought to determine if chief cell maturity is a limiting factor in the capacity to transdifferentiate. Mist1(−)(/−) mice,...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283902/ https://ncbi.nlm.nih.gov/pubmed/27881402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00326.2016 |
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