The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism
Azathioprine, a purine analogue, significantly suppressed the purine synthesis de novo of two gouty patients manifesting overproduction of uric acid, as well as three of four gouty patients who showed normal uric acid production. This suppression is taken as evidence that phosphoribosyl-pyrophosphat...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1967
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16695929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105643 |
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