The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism

Azathioprine, a purine analogue, significantly suppressed the purine synthesis de novo of two gouty patients manifesting overproduction of uric acid, as well as three of four gouty patients who showed normal uric acid production. This suppression is taken as evidence that phosphoribosyl-pyrophosphat...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Kelley, William N., Rosenbloom, Frederick M., Seegmiller, J. Edwin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1967
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16695929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105643
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