The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism

Azathioprine, a purine analogue, significantly suppressed the purine synthesis de novo of two gouty patients manifesting overproduction of uric acid, as well as three of four gouty patients who showed normal uric acid production. This suppression is taken as evidence that phosphoribosyl-pyrophosphat...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Kelley, William N., Rosenbloom, Frederick M., Seegmiller, J. Edwin
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1967
Θέματα:	Articles
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16695929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105643
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