Liver Xeno-Repopulation with Human Hepatocytes in Fah(−/−)Rag2(−/−) Mice after Pharmacological Immunosuppression

Functional human hepatocytes xeno-engrafted in mouse liver can be used as a model system to study hepatitis virus infection and vaccine efficacy. Significant liver xeno-repopulation has been reported in two kinds of genetically modified mice that have both immune deficiency and liver injury–induced...

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Detalhes bibliográficos
Main Authors: He, Zhiying, Zhang, Haibin, Zhang, Xin, Xie, Dongfu, Chen, Yixin, Wangensteen, Kirk J., Ekker, Stephen C., Firpo, Meri, Liu, Changcheng, Xiang, Dao, Zi, Xiaoyuan, Hui, Lijian, Yang, Guangshun, Ding, Xiaoyan, Hu, Yiping, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928964/
https://ncbi.nlm.nih.gov/pubmed/20651238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091154
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