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A genetic screen reveals Foxa3 and TNFR1 as key regulators of liver repopulation

The fundamental question of which genes are most important in controlling liver regeneration remains unanswered. We employed a parallel screen to test the impact of 43 selected genes on liver repopulation in the Fah(−/−) mouse model of hereditary tyrosinemia. We discovered that the transcription fac...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Wangensteen, Kirk J., Zhang, Sophia, Greenbaum, Linda E., Kaestner, Klaus H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421979/
https://ncbi.nlm.nih.gov/pubmed/25934503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.258855.115
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