PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

Fungal pathogens exploit diverse mechanisms to survive exposure to antifungal drugs. This poses concern given the limited number of clinically useful antifungals and the growing population of immunocompromised individuals vulnerable to life-threatening fungal infection. To identify molecules that ab...

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Hauptverfasser: LaFayette, Shantelle L., Collins, Cathy, Zaas, Aimee K., Schell, Wiley A., Betancourt-Quiroz, Marisol, Gunatilaka, A. A. Leslie, Perfect, John R., Cowen, Leah E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928802/
https://ncbi.nlm.nih.gov/pubmed/20865172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001069
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