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Hedgehog controls neural stem cells through p53-independent regulation of Nanog
Hedgehog (Hh) pathway has a pivotal function in development and tumorigenesis, processes sustained by stem cells (SCs). The transcription factor Nanog controls stemness acting as a key determinant of both embryonic SC self-renewal and differentiated somatic cells reprogramming to pluripotency, in co...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928686/ https://ncbi.nlm.nih.gov/pubmed/20581804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.131 |
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