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PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells
An important step in carcinoma progression is loss of cell-cell adhesion leading to increased invasion and metastasis. We show here that the protein tyrosine phosphatase, PTP-PEST, is a critical regulator of cell-cell junction integrity and epithelial cell motility. Using colon carcinoma cells, we s...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928632/ https://ncbi.nlm.nih.gov/pubmed/20519451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00148.2010 |
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