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Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of IκB kinases in mice: impact on histone acetylation

Glutaredoxin 1 (Glrx1) is a small dithiol protein that regulates the cellular redox state and redox-dependent signaling pathways via modulation of protein glutathionylation. IκB kinase (IKK), an essential enzyme for NF-κB activation, can be subjected to S-glutathionylation leading to alteration of i...

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Detaylı Bibliyografya
Asıl Yazarlar: Chung, Sangwoon, Sundar, Isaac Kirubakaran, Yao, Hongwei, Ho, Ye-Shih, Rahman, Irfan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928604/
https://ncbi.nlm.nih.gov/pubmed/20472709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00426.2009
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