PI(3,5)P(2) Controls Membrane Traffic by Direct Activation of Mucolipin Ca(2+) Release Channels in the Endolysosome

Membrane fusion and fission in intracellular trafficking is controlled by both intraluminal Ca(2+) release and phosphoinositide signaling. However, the molecular identities of the Ca(2+) release channels and the target proteins of phosphoinositides are elusive. Here, by direct patch-clamping of the...

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Bibliografiske detaljer
Main Authors: Dong, Xian-ping, Shen, Dongbiao, Wang, Xiang, Dawson, Taylor, Li, Xinran, Zhang, Qi, Cheng, Xiping, Zhang, Yanling, Weisman, Lois S., Delling, Markus, Xu, Haoxing
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928581/
https://ncbi.nlm.nih.gov/pubmed/20802798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1037
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