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Mucolipins: Intracellular TRPML1-3 Channels
The mucolipin family of Transient Receptor Potential (TRPML) proteins is predicted to encode ion channels expressed in intracellular endosomes and lysosomes. Loss-of-function mutations of human TRPML1 cause type IV mucolipidosis (ML4), a childhood neurodegenerative disease. Meanwhile, gain-of-functi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866799/ https://ncbi.nlm.nih.gov/pubmed/20074572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.12.056 |
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