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BH3-only proteins in apoptosis and beyond: an overview
BH3-only BCL-2 family proteins are effectors of canonical mitochondrial apoptosis. They discharge their pro-apoptotic functions through BH1-3 pro-apoptotic proteins such as BAX and BAK, while their activity is suppressed by BH1-4 anti-apoptotic BCL-2 family members. The precise mechanism by which BH...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928556/ https://ncbi.nlm.nih.gov/pubmed/19641503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.39 |
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