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Bisulfite Patch PCR enables multiplexed sequencing of promoter methylation across cancer samples
Aberrant DNA methylation frequently occurs at gene promoters during cancer progression. It is important to identify these loci because they are often misregulated and drive tumorigenesis. Bisulfite sequencing is the most direct and highest resolution assay for identifying aberrant promoter methylati...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928506/ https://ncbi.nlm.nih.gov/pubmed/20627893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.101212.109 |
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