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High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes

Using high-throughput sequencing, we devised a technique to determine the insertion sites of virtually all members of the human-specific L1 retrotransposon family in any human genome. Using diagnostic nucleotides, we were able to locate the approximately 800 L1Hs copies corresponding specifically to...

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Detalhes bibliográficos
Main Authors: Ewing, Adam D., Kazazian, Haig H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928504/
https://ncbi.nlm.nih.gov/pubmed/20488934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.106419.110
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