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Mechanisms of Mutation in Nondividing Cells: Insights from the Study of Adaptive Mutation in Escherichia coli

When populations of cells are subjected to nonlethal selection, mutations arise in the absence of cell division, a phenomenon that has been called “adaptive mutation.” In a strain of Escherichia coli that cannot metabolize lactose (Lac(−)) but that reverts to lactose utilization (Lac(+)) when lactos...

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Detalhes bibliográficos
Main Authors: Foster, Patricia L., Rosche, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928472/
https://ncbi.nlm.nih.gov/pubmed/10415479
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