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Increased episomal replication accounts for the high rate of adaptive mutation in recD mutants of Escherichia coli.

Adaptive mutation has been studied extensively in FC40, a strain of Escherichia coli that cannot metabolize lactose (Lac-) because of a frameshift mutation affecting the lacZ gene on its episome. recD mutants of FC40, in which the exonuclease activity of RecBCD (ExoV) is abolished but its helicase a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Foster, P L, Rosche, W A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460594/
https://ncbi.nlm.nih.gov/pubmed/10224241
Tagiau: Ychwanegu Tag
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