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Absence of the Caveolin-1 P132L Mutation in Cancers of the Breast and Other Organs
Caveolin-1 belongs to a family of scaffolding proteins, and the P132L point mutation of this gene has been found in up to 16% of all examined breast cancers. Subsequent studies have revealed that the P132L mutation exerts a dominant negative effect through misfolding during caveolin-1 oligomerizatio...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Investigative Pathology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928437/ https://ncbi.nlm.nih.gov/pubmed/20581046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090180 |
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