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Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy
Adoptive immunotherapy with tumor-specific T lymphocytes has demonstrated clinical benefit in some cancers, particularly melanoma. Yet isolating and expanding tumor-specific cells from patients is challenging, and there is limited ability to control T cell affinity and response characteristics. T ce...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928402/ https://ncbi.nlm.nih.gov/pubmed/20680493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-010-0090-1 |
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