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The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy

The TAM receptor protein tyrosine kinases—Tyro3, Axl, and Mer—are essential regulators of immune homeostasis. Guided by their cognate ligands Growth arrest-specific gene 6 (Gas6) and Protein S (Pros1), these receptors ensure the resolution of inflammation by dampening the activation of innate cells...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Paolino, Magdalena, Penninger, Josef M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082387/
https://ncbi.nlm.nih.gov/pubmed/27775650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8100097
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