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TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting
The TAM receptors—TYRO3, AXL, MERTK—are pleiotropically expressed receptors in both healthy and diseased tissue. A complex of the ligands Protein S (PROS1) or Growth Arrest-Specific 6 (GAS6) with apoptotic phosphatidylserine activates the TAM receptors. Hence, this receptor family is essential for t...
में बचाया:
| में प्रकाशित: | Cancer Immunol Immunother |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Springer Berlin Heidelberg
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000491/ https://ncbi.nlm.nih.gov/pubmed/31664482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02421-w |
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