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TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting
The TAM receptors—TYRO3, AXL, MERTK—are pleiotropically expressed receptors in both healthy and diseased tissue. A complex of the ligands Protein S (PROS1) or Growth Arrest-Specific 6 (GAS6) with apoptotic phosphatidylserine activates the TAM receptors. Hence, this receptor family is essential for t...
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| Publicat a: | Cancer Immunol Immunother |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000491/ https://ncbi.nlm.nih.gov/pubmed/31664482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02421-w |
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