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Dendritic cells continue to capture and present antigens after maturation in vivo

Dendritic cell (DC) maturation is critical for the regulation of T-cell responses. The down regulation of endocytosis upon maturation is considered a key adaptation that dissociates prior antigen capture by DCs from subsequent T-cell engagement. In order to study the dynamics of antigen capture and...

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Bibliografiske detaljer
Main Authors: Drutman, Scott B., Trombetta, E. Sergio
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928255/
https://ncbi.nlm.nih.gov/pubmed/20644175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000642
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