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In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells
Autophagy is known to be important in presentation of cytosolic antigens on MHC class II (MHC II). However, the role of autophagic process in antigen presentation in vivo is unclear. Mice with dendritic cell (DC)-conditional deletion in Atg5, a key autophagy gene, showed impaired CD4(+) T cell primi...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996467/ https://ncbi.nlm.nih.gov/pubmed/20171125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.12.006 |
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