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Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway

Malformations of cortical development are characteristic of a plethora of diseases that includes polymicrogyria, periventricular and subcortical heterotopia and lissencephaly. Mutations in TUBA1A and TUBB2B, each a member of the multigene families that encode α- and β-tubulins, have recently been im...

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Autors principals: Tian, Guoling, Jaglin, Xavier H., Keays, David A., Francis, Fiona, Chelly, Jamel, Cowan, Nicholas J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928131/
https://ncbi.nlm.nih.gov/pubmed/20603323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq276
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