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A Pachygyria-causing α-Tubulin Mutation Results in Inefficient Cycling with CCT and a Deficient Interaction with TBCB
The agyria (lissencephaly)/pachygyria phenotypes are catastrophic developmental diseases characterized by abnormal folds on the surface of the brain and disorganized cortical layering. In addition to mutations in at least four genes—LIS1, DCX, ARX and RELN—mutations in a human α-tubulin gene, TUBA1A...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262973/ https://ncbi.nlm.nih.gov/pubmed/18199681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0861 |
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