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MUTATIONS AFFECTING β-TUBULIN FOLDING AND DEGRADATION
Revertants of a colcemid resistant Chinese hamster ovary cell line with an altered (D45Y) β-tubulin have allowed the identification of 4 cis-acting mutations (L187R, Y398C, a 12 amino acid in-frame deletion, and a C-terminal truncation) that act by destabilizing the mutant tubulin and preventing it...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715149/ https://ncbi.nlm.nih.gov/pubmed/16554299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M513730200 |
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