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How cyclin A destruction escapes the spindle assembly checkpoint
The anaphase-promoting complex/cyclosome (APC/C) is the ubiquitin ligase essential to mitosis, which ensures that specific proteins are degraded at specific times to control the order of mitotic events. The APC/C coactivator, Cdc20, is targeted by the spindle assembly checkpoint (SAC) to restrict AP...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928024/ https://ncbi.nlm.nih.gov/pubmed/20733051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001083 |
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