טוען...
Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector
One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation. To minimize this damage, we have developed a brief transduction procedure for lentivirus vect...
שמור ב:
| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927804/ https://ncbi.nlm.nih.gov/pubmed/20485382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.62 |
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