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Differential effects of cisplatin and MNNG on dna mutants of Escherichia coli
DNA mismatch repair (MMR) in mammalian cells or Escherichia coli dam mutants increases the cytotoxic effects of cisplatin and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). We found that, unlike wildtype, the dnaE486 (alpha catalytic subunit of DNA polymerase III holoenzyme) mutant, and a DnaX (c...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927670/ https://ncbi.nlm.nih.gov/pubmed/16144703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2005.06.030 |
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