Distinguishing between cancer driver and passenger gene alteration candidates via cross-species comparison: a pilot study

BACKGROUND: We are developing a cross-species comparison strategy to distinguish between cancer driver- and passenger gene alteration candidates, by utilizing the difference in genomic location of orthologous genes between the human and other mammals. As an initial test of this strategy, we conducte...

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Detalhes bibliográficos
Main Authors: Ji, Xinglai, Tang, Jie, Halberg, Richard, Busam, Dana, Ferriera, Steve, Peña, Maria Marjorette O, Venkataramu, Chinnambally, Yeatman, Timothy J, Zhao, Shaying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927548/
https://ncbi.nlm.nih.gov/pubmed/20707908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-426
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