The C-terminus of interferon gamma receptor beta chain (IFNγR2) has antiapoptotic activity as a Bax inhibitor

Bax is a pro-apoptotic protein that mediates intrinsic cell-death signaling. Using a yeast-based functional screening approach, we identified interferon gamma receptor beta chain (IFNγR2) as a new Bax suppressor. IFNγR2 is a component of the IFNγ receptor complex along with the IFNγR alpha chain (IF...

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Autors principals: Gomez, Jose A., Sun, Weiyon, Gama, Vivian, Hajkova, Dagmar, Yoshida, Tomoyuki, Wu, Zhengrong, Miyagi, Masaru, Pink, John J., Jackson, Mark W., Danielpour, David, Matsuyama, Shigemi
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927208/
https://ncbi.nlm.nih.gov/pubmed/19657228
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