Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques

DNA vaccines have undergone important enhancements in their design, formulation, and delivery process. Past literature supports that DNA vaccines are not as immunogenic in nonhuman primates as live vector systems. The most potent recombinant vector system for induction of cellular immune responses i...

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Detalhes bibliográficos
Main Authors: Hirao, Lauren A, Wu, Ling, Satishchandran, Abhishek, Khan, Amir S, Draghia-Akli, Ruxandra, Finnefrock, Adam C, Bett, Andrew J, Betts, Michael R, Casimiro, Danilo R, Sardesai, Niranjan Y, Kim, J Joseph, Shiver, John W, Weiner, David B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927062/
https://ncbi.nlm.nih.gov/pubmed/20551910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.112
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