Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques

DNA vaccines have undergone important enhancements in their design, formulation, and delivery process. Past literature supports that DNA vaccines are not as immunogenic in nonhuman primates as live vector systems. The most potent recombinant vector system for induction of cellular immune responses i...

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Autors principals: Hirao, Lauren A, Wu, Ling, Satishchandran, Abhishek, Khan, Amir S, Draghia-Akli, Ruxandra, Finnefrock, Adam C, Bett, Andrew J, Betts, Michael R, Casimiro, Danilo R, Sardesai, Niranjan Y, Kim, J Joseph, Shiver, John W, Weiner, David B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927062/
https://ncbi.nlm.nih.gov/pubmed/20551910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.112
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