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Molecular recognition of protein surfaces: High affinity ligands for the CBP KIX domain
Potent and specific inhibitors of protein•protein interactions have significant potential both as therapeutic compounds and biological tools, yet discovery of such molecules remains a significant challenge. Whereas small molecules typically bind proteins in small, well-defined, deep clefts, proteins...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926944/ https://ncbi.nlm.nih.gov/pubmed/14624582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja034508o |
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