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Molecular recognition of protein surfaces: High affinity ligands for the CBP KIX domain

Potent and specific inhibitors of protein•protein interactions have significant potential both as therapeutic compounds and biological tools, yet discovery of such molecules remains a significant challenge. Whereas small molecules typically bind proteins in small, well-defined, deep clefts, proteins...

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Hlavní autoři: Rutledge, Stacey E., Volkman, Heather M., Schepartz, Alanna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926944/
https://ncbi.nlm.nih.gov/pubmed/14624582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja034508o
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