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Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain

Evidence suggests that increased glucocorticoid receptor (GR) signaling may contribute to cognitive decline with age. We hypothesized that alterations in GR signaling pathway molecules, FK506 binding protein (FKBP) 51 and FKBP52, were associated with memory impairment in aged mice. We used the singl...

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Bibliografiske detaljer
Main Authors: Soontornniyomkij, Virawudh, Risbrough, Victoria B., Young, Jared W., Wallace, Chelsea K., Soontornniyomkij, Benchawanna, Jeste, Dilip V., Achim, Cristian L.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926850/
https://ncbi.nlm.nih.gov/pubmed/20422297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-010-9145-9
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