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Age and High-Fat Diet Effects on Glutamine Synthetase Immunoreactivity in Liver and Hippocampus and Recognition Memory in Mice

BACKGROUND: High-fat diet (HFD)-induced obesity may promote age-related memory impairment via disturbances of ammonia-glutamine metabolism. OBJECTIVE: We studied the effects of age and long-term HFD exposure on glutamine synthetase (GS) expression in the liver and hippocampus and recognition memory...

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Detalhes bibliográficos
Publicado no:Curr Aging Sci
Main Authors: Soontornniyomkij, Virawudh, Kesby, James P., Soontornniyomkij, Benchawanna, Kim, Jane J., Kisseleva, Tatiana, Achim, Cristian L., Semenova, Svetlana, Jeste, Dilip V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063669/
https://ncbi.nlm.nih.gov/pubmed/27071478
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