Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail

Biosynthesis of aromatic amino acids in plants, many bacteria, and microbes relies on the enzyme 5-enolpyruvylshikimate 3-phosphate (EPSP) synthase, a prime target for drugs and herbicides. We have identified the interaction of EPSP synthase with one of its two substrates (shikimate 3-phosphate) and...

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Autors principals: Schönbrunn, Ernst, Eschenburg, Susanne, Shuttleworth, Wendy A., Schloss, John V., Amrhein, Nikolaus, Evans, Jeremy N. S., Kabsch, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC29264/
https://ncbi.nlm.nih.gov/pubmed/11171958
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