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Disruption of insulin-like growth factor-I expression in type IIαI collagen-expressing cells reduces bone length and width in mice
It is well established that insulin-like growth factor (IGF)-I is critical for the regulation of peak bone mineral density (BMD) and bone width. However, the role of systemic vs. local IGF-I is not well understood. To determine the role local IGF-I plays in regulating BMD and bone width, we crossed...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925693/ https://ncbi.nlm.nih.gov/pubmed/17519362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00022.2007 |
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