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Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites

In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia, and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought to determine whether A fumigatus directly modulates angiogenesis. A fumigatus culture filtrates profoundly inhibited t...

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Bibliografische gegevens
Hoofdauteurs: Ben-Ami, Ronen, Lewis, Russell E., Leventakos, Konstantinos, Kontoyiannis, Dimitrios P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925388/
https://ncbi.nlm.nih.gov/pubmed/19843884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231209
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