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Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites

In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia, and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought to determine whether A fumigatus directly modulates angiogenesis. A fumigatus culture filtrates profoundly inhibited t...

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Hlavní autoři: Ben-Ami, Ronen, Lewis, Russell E., Leventakos, Konstantinos, Kontoyiannis, Dimitrios P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925388/
https://ncbi.nlm.nih.gov/pubmed/19843884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231209
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