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Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites
In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia, and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought to determine whether A fumigatus directly modulates angiogenesis. A fumigatus culture filtrates profoundly inhibited t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925388/ https://ncbi.nlm.nih.gov/pubmed/19843884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231209 |
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