Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites

In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia, and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought to determine whether A fumigatus directly modulates angiogenesis. A fumigatus culture filtrates profoundly inhibited t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ben-Ami, Ronen, Lewis, Russell E., Leventakos, Konstantinos, Kontoyiannis, Dimitrios P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2009
Pynciau:
Vascular Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925388/
https://ncbi.nlm.nih.gov/pubmed/19843884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231209
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