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Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study
BACKGROUND: Cathepsins represent a group of proteases involved in determining the metastatic potential of cancer cells. Among these are cysteinyl- (e.g. cathepsin B and cathepsin L) and aspartyl-proteases (e.g. cathepsin D), normally present inside the lysosomes as inactive proenzymes. Once released...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925371/ https://ncbi.nlm.nih.gov/pubmed/20684763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-207 |
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