Kv4.2 knockout mice demonstrate increased susceptibility to convulsant stimulation

PURPOSE: Kv4.2 subunits contribute to the pore-forming region of channels that express a transient, A-type K(+) current (A-current) in hippocampal CA1 pyramidal cell dendrites. Here, the A-current plays an important role in signal processing and synaptic integration. Kv4.2 knockout mice show a near...

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Bibliographic Details
Main Authors:	Barnwell, L. Forbes S., Lugo, Joaquin N., Lee, Wai Ling, Willis, Sarah E., Gertz, Shira J., Hrachovy, Richard A., Anderson, Anne E.
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2925051/ https://ncbi.nlm.nih.gov/pubmed/19453702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2009.02086.x
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Kv4.2 knockout mice demonstrate increased susceptibility to convulsant stimulation

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