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Kv4.2 knockout mice display learning and memory deficits in the Lashley maze

Background: Potassium channels have been shown to be involved in neural plasticity and learning. Kv4.2 is a subunit of the A-type potassium channel. Kv4.2 channels modulate excitability in the dendrites of pyramidal neurons in the cortex and hippocampus. Deletion of Kv4.2 results in spatial learning...

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Pubblicato in:F1000Res
Autori principali: Smith, Gregory D., Gao, Nan, Lugo, Joaquin N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000Research 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247778/
https://ncbi.nlm.nih.gov/pubmed/28163893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9664.2
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