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Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus

Extracelluar signal-regulated kinase (ERK) pathway activation has been demonstrated following convulsant stimulation; however, little is known about the molecular targets of ERK in seizure models. Recently, it has been shown that ERK phosphorylates Kv4.2 channels leading to down-regulation of channe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lugo, Joaquin N., Barnwell, Lyndon Forbes, Ren, Yajun, Lee, Wai Ling, Johnston, Lisa Danielle, Kim, Rebecca, Hrachovy, Richard A., Sweatt, John David, Anderson, Anne E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678944/
https://ncbi.nlm.nih.gov/pubmed/18513371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05508.x
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