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Corecognition of DNA and a methylated histone tail by MSL3 chromodomain
MSL3 resides in the MSL (male-specific-lethal) complex that upregulates transcription by spreading the H4K16 acetyl-mark. We discovered a DNA-dependent interaction of MSL3 chromodomain with the histone H4K20 monomethyl-mark. Structure of a ternary complex shows DNA minor groove accommodates the hist...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924628/ https://ncbi.nlm.nih.gov/pubmed/20657587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1856 |
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