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Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells

BACKGROUND: Src family kinases (SFK) collectively regulate a variety of cellular functions in many cancer types, including proliferation, invasion, motility, survival, differentiation, and angiogenesis. Although Dasatinib (BMS-354825), an ATP-competitive, small molecule tyrosine kinase inhibitor, su...

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Detalhes bibliográficos
Main Authors: Premkumar, Daniel R., Jane, Esther P., Agostino, Naomi R., Scialabba, Joseph L., Pollack, Ian F.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924609/
https://ncbi.nlm.nih.gov/pubmed/20808823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.65448
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