Survivin Inhibitor YM-155 Sensitizes Tumor Necrosis Factor– Related Apoptosis-Inducing Ligand-Resistant Glioma Cells to Apoptosis through Mcl-1 Downregulation and by Engaging the Mitochondrial Death Pathway

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• YM-155 potentiates the effect of ABT-737 in malignant human glioma cells via survivin and Mcl-1 downregulation in an EGFR-dependent context
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• Survivin Inhibitor YM155 Induces Mitochondrial Dysfunction, Autophagy, DNA Damage, and Apoptosis in Bcl-xL Silenced Glioma Cell Lines
  gan: Jane, Esther P., et al.
  Cyhoeddwyd: (2016)
• YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation
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  Cyhoeddwyd: (2020)
• NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5
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  Cyhoeddwyd: (2015)
• Silencing of survivin by YM155 induces apoptosis and growth arrest in hepatocellular carcinoma cells
  gan: ZHANG, CHANGHE, et al.
  Cyhoeddwyd: (2015)